Cipro Drug Information

How should I take Cipro?

• Take Cipro exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent the formation of Cipro crystals in the urine.
• Shake the oral suspension vigorously for 15 seconds before each use. Do not chew the microcapsules in the suspension, swallow them whole.
• Do not crush, break, or chew the CIPRO XR tablets. Swallow them whole. They are specially formulated to release the medication slowly in the body.
• Cipro may be taken with or without food. It is preferable to take Cipro 2 hours after a meal.
• Do not take Cipro with dairy products (such as milk or yogurt) or calcium-fortified juice alone. It is not a problem if Cipro is taken with dietary calcium in a normal meal, but when taken only with dairy products or calcium-fortified juice, the effectiveness of the medication may be decreased.
• Take Cipro at evenly spaced intervals.
• Do not take antacids that contain calcium, magnesium or aluminum (e.g., Tums or Rolaids); the ulcer medicine sucralfate (Carafate); or vitamin or mineral supplements that contain calcium, iron or zinc for a minimum of 6 hours before or 2 hours after a dose of Cipro. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of Cipro can greatly decrease the effects of the antibiotic.
• Take all of the Cipro that has been prescribed for you even if you begin to feel better. Symptoms may start to improve before the infection is completely treated.
• Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention.

The most common symptom of a Cipro overdose is seizures.

What should I avoid while taking Cipro?

• Avoid prolonged exposure to sunlight. Cipro may increase the sensitivity of the skin to sunlight, and a sunburn may result. If sun exposure is unavoidable, wear protective clothing and use a sunscreen. Call your doctor if you experience severe burning, redness, itching, rash, or swelling after exposure to the sun.
• Use caution when driving, operating machinery, or performing other hazardous activities. Cipro may cause dizziness. If you experience dizziness, avoid these activities.
• Avoid excessive consumption of products that contain caffeine. Cipro may increase the effects of caffeine.

What are the possible side effects of Cipro?

If you experience any of the following serious side effects, stop taking Cipro and seek emergency medical attention or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
• seizures
• confusion or hallucinations
• liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue)
• muscle or joint pain
• skin rash
• chest pain, chest discomfort, shortness of breath , or swelling of the legs or feet

If you experience any of the following less serious side effects, continue taking Cipro and talk to your doctor:

• nausea, vomiting, diarrhea
• headache
• dizziness or lightheadedness
• drowsiness
• insomnia
• ringing in the ears
• increased sensitivity of the skin to sunlight

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Cipro?

Do not take antacids that contain calcium, magnesium or aluminum (e.g., Tums or Rolaids); the ulcer medicine sucralfate (Carafate); or vitamin or mineral supplements that contain calcium, iron or zinc for a minimum of 6 hours before or 2 hours after a dose of Cipro. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of Cipro can greatly decrease the effects of the antibiotic.

Before taking Cipro, tell your doctor if you are taking any of the following drugs:

• didanosine (Videx, ddI)
• theophylline (Theo-Dur, Theolair, Slo-Phyllin, Slo-Bid, Elixophyllin)
• warfarin (Coumadin)
• probenecid (Benemid)
• insulin or an oral diabetes medication such as glipizide (Glucotrol), glyburide (Micronase, Diabeta, Glynase), and others
• a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin, others), naproxen (Aleve, Naprosyn, Anaprox), ketoprofen (Orudis KT, Orudis, Oruvail), and others
• phenytoin (Dilantin)
• cyclosporine (Neoral, Sandimmune)

You may not be able to take Cipro, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with Cipro. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.