Xanthigen Reviews
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Xanthigen is a weight loss formula that was first created in Russia. As it is a proprietary recipe, the manufacturers have not released the ingredients list for the drug, which is always sketchy, as it makes one wonder what it is that the company has to hide. What is known about the drug, though, is that it contains fucoxanthin in an unknown quantity, and that there have been studies on the drug itself, which is rare for many kinds of weight loss supplement currently on the market.
Xanthigen Research
Among the studies that have shown the results of the drug is “The Effects of Xanthigen™ in the Weight Management of Obese Premenopausal Women With Non-Alcoholic Fatty Liver Disease and Normal Liver Fat” as was published in the October 13, 2009 issue of the Diabetes, Obesity and Metabolism journal (Volume 12, Issue 1, pages 72-81) by Musa Abidov et al. Within this study, the drug was examined and it was revealed that its ingredients include:
- Brown marine algae fucoxanthin
- Pomegranate seed oil (PSO)
The study examined the impact on the body’s fat, weight, biochemistry of the blood, and liver lipids as well as the effect of the individual elements of the medicine on the resting energy expenditure (REE) within 151 obese women who were not diabetic and who had non-alcoholic fatty liver disease (NAFLD) with normal liver fat (NLF) levels. It was a randomized, double-blind, placebo-controlled study of sixteen weeks in length. What the study discovered is that Xanthigen 600/2.4mg did indeed allow for a decrease in body weight that was statistically significant, including a lowered waist circumference and lowered liver fat content. The REE increased significantly within the subjects taking Xanthigen when compared to the placebo participants. Exclusive rights to Xanthigen belong to National Bioscience Corporation. The formula for the drug is patent-pending. The National Bioscience Corporation has brought Xanthigen to North America for sale as a weight loss supplement.
Fucoxanthin is Thought to Be the Magic Behind the Formula
It is believed that it is the fucoxanthin content of the formula that is responsible for the weight loss results seen in the studies. For that ingredient alone, most studies have been conducted on animals. There have been a few studies on humans, but they are very limited and further study is needed to determine the true safety and efficacy in humans. That said, in animal studies, abdominal fat loss was recorded in the results of rats and mice, typically losing between five and ten percent of their overall body weight. The fucoxanthin substance is isolated from wakame, which is found in certain types of seaweed. As of yet, it is not completely understood how fucoxanthin actually works, but it is believed that the UCP1 protein (one responsible for the speed at which fat in the abdomen is burned) is targeted by the substance. Further study is still required to determine whether this is actually the ingredient behind the results seen in some Xanthigen users and whether or not it has any associated side effects or risks – facts that have not yet been fully determined.
June 2020 Update
As of June 2020, Xanthigen is still around and is a patented clinically studied propriety weight management formulation from Spain-based Nektium Pharma. The company holds GMP certification and FSSC 22000 Food Safety System Certification by SGS. That said, the statements the company has made about this patented ingredient have not been evaluated by the FDA. Nektium’s Xanthigen is a composed of:
- Fucoxanthin (brown seaweed)
- Punicic acid (pomegranate seed oil)
According to the official Netium website, its key benefits include:
- Increasing brown adipose tissue
- Suppresses lipid accumulation
- Lowers body and liver fat
All that said, there is no concrete clinical proof that Xanthigen is any more effective for weight management now than it was when it was first introduced to the market. The fact remains that human clinical trials are lacking. Simply because an ingredient is patented does not mean that it is effective or that it can live up to its claims. It is strongly recommended that if you are considering taking any OTC diet pill that contains Xanthigen that you first consult with your healthcare provider before you take it, especially if you have an existing medical condition for which you are being treated.